Biopython up to 186 Bio.Entrez xml external entity reference
| CVSS Meta Temp Score | Current Exploit Price (≈) | CTI Interest Score |
|---|---|---|
| 5.0 | $0-$5k | 0.00 |
Summary
A vulnerability, which was classified as problematic, was found in Biopython up to 186. This affects an unknown function of the component Bio.Entrez. Such manipulation leads to xml external entity reference. This vulnerability is documented as CVE-2025-68463. The attack can be executed remotely. There is not any exploit available.
Details
A vulnerability was found in Biopython up to 186 and classified as problematic. Affected by this issue is some unknown functionality of the component Bio.Entrez. The manipulation with an unknown input leads to a xml external entity reference vulnerability. Using CWE to declare the problem leads to CWE-611. The product processes an XML document that can contain XML entities with URIs that resolve to documents outside of the intended sphere of control, causing the product to embed incorrect documents into its output. Impacted is confidentiality, integrity, and availability.
The advisory is shared for download at github.com. This vulnerability is handled as CVE-2025-68463 since 12/18/2025. The exploitation is known to be difficult. The attack may be launched remotely. There are neither technical details nor an exploit publicly available.
The vulnerability scanner Nessus provides a plugin with the ID 279104 (Linux Distros Unpatched Vulnerability : CVE-2025-68463), which helps to determine the existence of the flaw in a target environment.
There is no information about possible countermeasures known. It may be suggested to replace the affected object with an alternative product.
The vulnerability is also documented in the vulnerability database at Tenable (279104). VulDB is the best source for vulnerability data and more expert information about this specific topic.
Product
Type
Name
Version
Website
CPE 2.3
CPE 2.2
CVSSv4
VulDB Vector: 🔒VulDB Reliability: 🔍
CVSSv3
VulDB Meta Base Score: 5.0VulDB Meta Temp Score: 5.0
VulDB Base Score: 5.0
VulDB Temp Score: 5.0
VulDB Vector: 🔒
VulDB Reliability: 🔍
CNA Base Score: 4.9
CNA Vector (MITRE): 🔒
CVSSv2
| AV | AC | Au | C | I | A |
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| 💳 | 💳 | 💳 | 💳 | 💳 | 💳 |
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| Vector | Complexity | Authentication | Confidentiality | Integrity | Availability |
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VulDB Base Score: 🔒
VulDB Temp Score: 🔒
VulDB Reliability: 🔍
Exploiting
Class: Xml external entity referenceCWE: CWE-611 / CWE-610
CAPEC: 🔒
ATT&CK: 🔒
Physical: No
Local: No
Remote: Yes
Availability: 🔒
Status: Not defined
EPSS Score: 🔒
EPSS Percentile: 🔒
Price Prediction: 🔍
Current Price Estimation: 🔒
| 0-Day | Unlock | Unlock | Unlock | Unlock |
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| Today | Unlock | Unlock | Unlock | Unlock |
Nessus ID: 279104
Nessus Name: Linux Distros Unpatched Vulnerability : CVE-2025-68463
Threat Intelligence
Interest: 🔍Active Actors: 🔍
Active APT Groups: 🔍
Countermeasures
Recommended: no mitigation knownStatus: 🔍
0-Day Time: 🔒
Timeline
12/18/2025 Advisory disclosed12/18/2025 CVE reserved
12/18/2025 VulDB entry created
12/18/2025 VulDB entry last update
Sources
Product: github.comAdvisory: 5109
Status: Confirmed
CVE: CVE-2025-68463 (🔒)
GCVE (CVE): GCVE-0-2025-68463
GCVE (VulDB): GCVE-100-337136
Entry
Created: 12/18/2025 08:44Updated: 12/18/2025 21:35
Changes: 12/18/2025 08:44 (62), 12/18/2025 21:35 (2)
Complete: 🔍
Cache ID: 216::103
VulDB is the best source for vulnerability data and more expert information about this specific topic.
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